First Successful Appendectomy In U.S. Was Performed In Eastern Iowa 137 Years AgoFirst Successful Appendectomy In U.S. Was Performed In Eastern Iowa 137 Years AgoDr. William West Grant performed the first successful appendectomy in the U.S. on a 22-year-old school teacher. The procedure happened on January 4th, 1885.Connor KenneyConnor Kenney